The quest for life beyond Earth is entering a transformative era, driven by powerful telescopes capable of scrutinizing the atmospheres of exoplanets for 'biosignatures' – chemical indicators that suggest biological activity. The James Webb Space Telescope (JWST) has emerged as a groundbreaking instrument in this endeavor, providing unprecedented data from distant worlds. Its observations have revealed tantalizing clues, such as the tentative detection of dimethyl sulfide (DMS) in the atmosphere of exoplanet K2-18b, a 'Hycean world' potentially rich in water and a hydrogen-rich atmosphere. While DMS is predominantly produced by marine life on Earth, scientists emphasize that these findings are not definitive proof of alien life and require further verification to rule out non-biological explanations. Beyond JWST, a fleet of upcoming telescopes and missions is poised to significantly advance the search. These include the proposed Habitable Worlds Observatory (HWO), designed to directly image Earth-sized planets and search for biosignatures like oxygen and methane. The Large Interferometer for Exoplanets (LIFE), a concept involving multiple satellites working in unison, aims to detect bioindicative chemicals such as ozone, methane, and nitrous oxide in the mid-infrared spectrum. Other planned missions like NASA's Pandora, Ariel, Plato, and the Nancy Grace Roman Space Telescope will further contribute by studying exoplanet atmospheres, identifying planetary shadows, and disentangling stellar signals from planetary ones. The scientific community underscores the need for a collaborative approach, combining advanced observational techniques with laboratory experiments and computational simulations, to accurately interpret the complex atmospheric data and determine whether detected chemicals are indeed signs of life. This global scientific endeavor represents humanity's persistent drive to understand its place in the cosmos.