The claim that vaccination and screening 'could end cervical cancer' is accurate and strongly supported by global health organizations and scientific evidence. The World Health Organization (WHO) launched a Global Strategy for cervical cancer elimination in 2020, setting ambitious 90-70-90 targets to be met by 2030: 90% of girls fully vaccinated with the HPV vaccine by age 15, 70% of women screened using a high-performance test by ages 35 and 45, and 90% of women with pre-cancer treated and 90% of women with invasive cancer managed. Achieving these targets is projected to significantly reduce incidence rates and avert millions of deaths worldwide. HPV vaccination is a highly effective primary prevention method, with studies showing a dramatic reduction in cervical cancer cases, particularly among those vaccinated before age 17. For instance, vaccination by age 16 is associated with an 80% reduction in risk for cervical cancer, with some studies showing no cervical cancers detected in vaccinated cohorts when administered early. Moreover, recent research confirms the long-term protection offered by HPV vaccines. Cervical cancer screening, through methods like Pap tests and HPV DNA testing, serves as a crucial secondary prevention strategy. It allows for the detection and treatment of precancerous lesions before they develop into invasive cancer. Updated guidelines, including those from the HRSA in January 2026, increasingly recommend HPV testing as the preferred screening modality and now support self-collected HPV samples, which can significantly improve accessibility and screening rates. For India, where cervical cancer remains a significant public health burden, claiming a woman's life every eight minutes, widespread HPV vaccination and strengthened screening programs are critical. Health experts in India emphasize that with timely intervention, cervical cancer is almost 100% preventable. Implementing a national HPV vaccination strategy and transitioning to more effective screening methods like HPV-DNA testing with self-sampling are essential steps to curb the disease's prevalence in the country.