Precision Immunotherapy Improves Organ Function in Sepsis Patients

A recent multinational clinical trial indicates that add-on precision immunotherapy significantly improves organ dysfunction in sepsis patients by day nine, though it did not show a reduction in short-term mortality. This targeted approach, tailored to specific immune dysfunctions, offers a promising direction for sepsis treatment.

• Precision immunotherapy improved organ dysfunction in sepsis by day 9.
• Study stratified sepsis patients by specific immune dysregulation types.
• No significant difference observed in 28- and 90-day mortality.
• Treatment tailored using anakinra or interferon-gamma based on immune profile.
• Trial involved 276 patients across six countries.
• Sepsis remains a critical health burden, especially in India.

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