WHO Emphasizes CD4 Testing to Identify Advanced HIV Disease

The WHO strongly recommends CD4 testing to identify advanced HIV disease (AHD), defined by a CD4 count below 200 cells/mm³ or WHO clinical stage 3 or 4. This is crucial for delivering a comprehensive care package to reduce mortality.

• WHO stresses CD4 testing to pinpoint advanced HIV disease.
• AHD is defined by CD4 count <200 cells/mm³ or WHO stage 3/4.
• Critical for adults, adolescents, and children under five.
• Enables targeted interventions like rapid ART initiation and prophylaxis.
• CD4 count guides treatment decisions and opportunistic infection prevention.
• Recommendation is part of the updated 2025 WHO guidelines.

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