Lupus and Hives: New Insights into Co-occurrence and Risk Factors

A recent study highlights that chronic spontaneous urticaria (CSU) in systemic lupus erythematosus (SLE) patients does not signify higher lupus disease activity. Instead, it is associated with distinct clinical and laboratory risk factors, urging clinicians to interpret CSU within a broader patient context.

• Chronic urticaria in lupus patients not linked to increased disease activity.
• Study identified specific clinical and lab risk factors for CSU in SLE.
• Key factors include elevated immunoglobulins, mucosal ulcers, cylindruria.
• Clinicians advised against solely assuming lupus flare based on CSU presence.
• CSU is a known comorbidity with Systemic Lupus Erythematosus.
• Patients with chronic urticaria face a five-fold increased SLE risk.

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